Assistant Professor, Department of Pharmaceutical Sciences

South Dakota State University
College of Pharmacy
Box 2202C
Brookings, SD 57007
Phone: (605) 688-6126
Fax: (605) 688-5993
E-mail: Teresa.Seefeldt@sdstate.edu

B.S. Pharmaceutical Sciences, South Dakota State University
Pharm.D., South Dakota State University
Ph.D. Pharmaceutical Sciences, South Dakota State University

Teaching Areas and Courses:

Pharmacology (PHA 321)

Research Interests:

Modulation of cancer resistance to chemotherapy and radiation therapy
Development of novel anticancer agents

Publications:

Seefeldt T, Dwivedi C, Peitz G, Herman J, Carlson L, Zhang Z, Guan X. 2-Acetylamino-3-[4-(2-acetylamino-2-carboxy-ethylsulfanylcarbonylamino)-phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors. J Med Chem. 48: 5224-5231 (2005).

Guan X, Dwivedi C, Kim SY, Fine T, Ratzsch A, Seefeldt T, Peitz G, Zhang Z. Independent ability of rat kidney for the mercapturic acid biosynthesis of 1-chloro-2,4-dinitrobenzene. Current Topics in Toxicology 1: 153-160 (2004).

Active Research Projects:

Development of novel glutathione reductase inhibitors.

Investigation of glutathione reductase inhibition as a means of increasing cancer sensitivity to chemotherapy and radiation therapy.

2-Acetylamino-3-arylcarbamoylsulfanylpropionic acids as a novel class of anticancer drugs.

Professional Memberships:

American Chemical Society
American Association of Pharmaceutical Scientists
American Pharmacists Association
American Association for Cancer Research
American Association of Colleges of Pharmacy
Rho Chi
Phi Lambda Sigma
Kappa Epsilon

Honors and Awards

College of Pharmacy Teacher of the Year (2006)
South Dakota Board of Regents Excellence in eLearning Award (2007)